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Suhagra 50 mg tablet Citation: DePasquale, Charles (May 11, 2004). "HGH, HGH Use, and Sudden Death" Journal of Medical Toxicology, Volume 8, Number 4, pages 255-258. "The potential risk of non-steroidal selective estrogen receptor modulators (SERMs) in the U.S. population is a matter of public concern. This report is based on a study conducted by the National Toxicology Program in which an extensive literature review was performed and human subjects from the National Institutes of Health were interviewed in an effort to obtain information concerning SERM use in the National Health and Nutrition Examination Survey III population. SERMs are a group of compounds with broad range biological actions. There is a widespread use of these agents to treat a wide variety of conditions including menopausal symptoms, metabolic disorders (insulin resistance and obesity), the treatment of cancer, asthma, and hepatitis. Serum concentrations of these compounds are known to be on the rise in U.S. population. SERMs are considered to be safe when administered in therapeutic doses; however, potential for adverse effects exists with usage at these doses. This report presents preliminary results from the National Toxicology Program study that evaluated SERM exposure in U.S. Suhagra 50 mg for female adults. The study was performed in association with the National Institutes of Health Task Force on the Effects of Natural and Synthetic Substances. The results of study suggest that the general population is being exposed to SERM concentrations that exceed the U.S. Environmental Protection Agency's (EPA) safety limits for in the workplace." "The human hormonal system, however, has evolved to cope with these compounds. Although the acute effects of some SERMs are reversible within hours, the effects of sustained exposure to SERMs, especially at higher doses, can continue long after the acute effects have dissipated. potential for long-term adverse effects of SERMs includes obesity-related metabolic dysfunction, increased risk for cardiovascular and metabolic diseases, increased cancer risk. The possibility of SERM-related cancers is primary interest, but there little information concerning a similar possibility in men. The overall concern with SERMs is that they may induce changes in the body that are adverse to health or cause effects an unborn child, in addition to the health effects of drugs themselves." In a review of the evidence, US Food and Drug Administration (FDA) concludes that there is no evidence as of yet demonstrating the health risks associated with administration of these drugs. "These medications do not appear to affect the normal functioning of hormonal system and have been used successfully in the treatment of menopausal symptoms, weight management, and certain types of endocrine disorders. Because the potential for adverse health effects, they are not recommended as first-line treatment for these conditions." From the FDA's website, on use of HGH and analogs as male contraception: "When used for contraception, hGH or analogs are given by injection; however, they have been approved by the FDA for use intravenous injection in men of all ages and testosterone levels, up to the therapeutic range. HGH or analogs may be used as a male contraceptive if it is administered to the patient only intermittently in form of a shot or slow release tablet to minimize the effect on his natural body hormone levels. The dose of hGH or analog may need to be adjusted periodically. If these preparations are used in women, it generally takes between three and six months before they are effective for contraceptive use. If HGH is used in men, the best methods for use in preventing pregnancy have not yet been determined." From the FDA's website on HGH and analogs as male contraceptives, concerning the use of drugs for male contraception: "HGH is not approved as a male contraceptive, but it has been approved as a treatment for obesity, insulin resistance, and some types of cancers. Therefore, a physician may prescribe hGH for these conditions, or any other disease condition for which it is indicated, provided that there no serious conflict of interest or that the physician knows about availability of an alternative treatment that may be safer and more effective." From the FDA's website on HGH and analogs as male contraceptives, concerning the use of drugs for male contraception: "HGH is not approved as a male contraceptive, but it has been approved as a treatment for obesity, insulin resistance, and some types of cancers. Therefore, a physician may prescribe hGH for these conditions, or any other disease condition for which it is indicated, provided that there no serious conflict of interest or that the physician knows about availability of an alternative treatment that may be safer and more effective." In a review of the literature, FDA concluded that HGH (and a related hormone, IGF-1) has been used for benign prostatic hyper.

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